A Stunning Medical Breakthrough

In a remarkable advancement for breast cancer treatment, BriaCell Therapeutics Corp. has proudly announced the complete resolution of lung metastasis in a 78-year-old woman suffering from hormone receptor positive (HR+) breast cancer. This incredible outcome was confirmed just four months after the patient began the Bria-OTS™ immunotherapy, a personalized, off-the-shelf treatment currently being evaluated in clinical trials.

Details of the Innovative Treatment

Initially reported in February 2025, the positive results emerged after the patient underwent a series of Bria-OTS intradermal injections. Following only two months of targeted therapy, imaging confirmed that the lung tumor had disappeared completely. By the four-month mark, the patient not only retained a tumor-free status in her lungs but also exhibited stable disease elsewhere in her body.

A Beacon of Hope for Patients

Dr. Neal S. Chawla, a prominent oncologist and principal investigator for the Bria-OTS study, expressed his enthusiasm over the promising results, especially given that many patients with HR+ disease face limited options despite recent advancements in cancer treatments. "We are thrilled with our initial data demonstrating rapid and robust anti-tumor activity in this patient," he noted, looking forward to further investigations in metastatic breast cancer and additional cancer types.

A New Era in Cancer Therapy!

BriaCell's President and CEO, Dr. William V. Williams, hailed this unprecedented anti-cancer response as a significant milestone, showcasing the potential of the Bria-OTS personalized immunotherapy approach. This treatment represents a next-generation development of BriaCell’s previous candidate, Bria-IMT™, which is currently in pivotal Phase 3 trials for metastatic breast cancer.

Looking Ahead

With Bria-OTS under investigation in ongoing Phase 1/2a trials, the company aims to explore its efficacy not only as a standalone treatment but also in combination with immune checkpoint inhibitors, thus paving the way for new hope in oncology.

In Conclusion

The fight against cancer continues to evolve, and BriaCell's innovative therapies are leading the charge toward more effective, personalized solutions. This ground-breaking resolution of lung metastasis is not just a victory for one patient but a beacon of hope for many in the battle against breast cancer and beyond!