As NFL Week 5 approaches, fantasy football enthusiasts are eager to uncover the most promising picks for their lineups.

Last week, Green Bay Packers' quarterback Jordan Love showcased impressive stats in his return from a knee injury, completing 32 of 54 passes for 389 yards, along with four touchdowns and three interceptions in a nail-biting loss against the Minnesota Vikings. But with the Packers set to face the Los Angeles Rams, whose shaky defense allows an alarming average of 385.3 yards per game (ranking 31st in the league), the burning question remains: Can Love lead your fantasy squad to victory this week, or should you pivot to alternatives like Baker Mayfield, Sam Darnold, or Andy Dalton?

Why Expert Rankings Matter

Reliable fantasy football rankings can be invaluable in making those tricky start-sit decisions. In the world of fantasy football, even a single choice can determine whether you dominate your league or find yourself lamenting over missed opportunities. For several years, SportsLine's computer model has outperformed human experts, consistently identifying key players who could turn the tide of a fantasy season. These insights have proven particularly beneficial in recognizing talent ahead of their breakout performances—think A.J. Brown, Jonathan Taylor, and Christian McCaffrey.

SportsLine has simulated the entire NFL Week 5 schedule an astonishing 10,000 times to generate its latest fantasy rankings. Here’s a breakdown of the top performers you should consider for your fantasy lineups.

Top Fantasy Football QB Rankings for Week 5

1. **Lamar Jackson (Baltimore Ravens)**: In a commanding win against the Bills, Jackson completed 13 of 18 passes for 156 yards, also rushing for 54 yards and scoring once on the ground. With a prime matchup against a Bengals defense allowing 326.8 passing yards per game, he’s set for another standout performance.

2. **Brock Purdy (San Francisco 49ers)**: Purdy boasts an impressive completion rate of 68.9%, recently throwing for over 288 yards in his last three games. Facing off against the struggling Arizona Cardinals, who just conceded 42 points to the Commanders, he’s poised for a productive outing.

3. **Josh Allen (Buffalo Bills)**: After a lackluster performance against the Ravens, Allen will be looking to rebound against the Texans. His track record suggests he has the potential to exceed expectations following his first turnover of the season.

Top Fantasy Football RB Rankings for Week 5

1. **Derrick Henry (Baltimore Ravens)**: Henry has been extraordinary, racking up 480 yards and five touchdowns, including a remarkable 199-yard performance last week. His dominance is undeniable as he takes on a defense that will struggle to contain him.

2. **Jordan Mason (San Francisco 49ers)**: Filling in for the injured Christian McCaffrey, Mason has gained significant traction with consistent performances. Expect him to continue his workload against a vulnerable Cardinals defense.

3. **Kyren Williams (Los Angeles Rams)**: Williams is emerging as a reliable option, finding the end zone six times this season. He’ll look to maintain that momentum as he faces a leaky Packers defense.

Top Fantasy Football WR Rankings for Week 5

1. **Deebo Samuel (San Francisco 49ers)**: Returning from injury, Samuel’s potential is on the rise, particularly against a Cardinals' secondary that he has previously exploited.

2. **Jayden Reed (Green Bay Packers)**: Reed stepped up significantly in the loss to the Vikings, and facing a Rams team with a questionable secondary could lead to another strong performance.

3. **CeeDee Lamb (Dallas Cowboys)**: After a productive game against the Giants, Lamb seeks his first 100-yard performance this year against the Steelers, a hurdle he’s certainly capable of overcoming.

Top Fantasy Football TE Rankings for Week 5

1. **George Kittle (San Francisco 49ers)**: Boasting a significant snap share, Kittle has been crucial for the Niners and is expected to find the end zone again as he gears up against the Cardinals.

2. **Travis Kelce (Kansas City Chiefs)**: Coming off a stellar performance last week, Kelce aims to continue his success against the Saints in a highly anticipated matchup.

3. **Brock Bowers (Las Vegas Raiders)**: Though he hasn’t found the end zone yet, Bowers remains integral to the Raiders' passing game and could break out anytime soon.

Top Fantasy Football Defense Rankings for Week 5

1. **Vikings D/ST**: With an impressive average of just 14.8 points allowed per game and a strong interception record, they face a Jets squad that’s struggling offensively.

2. **Seahawks D/ST**: Despite a rough outing last week, they’ll take on a Giants offense averaging only 15 points per game, making them an intriguing start.

3. **Broncos D/ST**: After a strong showing against the Jets, the Broncos' defense has proven to be formidable this season as they gear up to face the Raiders.

Get Ahead in Your Fantasy League

Now that you’re armed with the top choices for each position, explore SportsLine for comprehensive Week 5 Fantasy Football rankings. Don’t miss out on crucial insights that could set you apart in your league. The fantasy football world is rife with surprises—discovering that hidden gem could be the key to your championship run!