The Genetic Basis of Body Odor

Body odor might not just be about what you eat or how much you sweat – it could be rooted deep within your DNA! Renowned dermatologists have recently uncovered that our genetic makeup plays a pivotal role in determining not only how much we perspire but also how odoriferous that sweat may be.

Dr. Heather Kornmehl, a dermatologist based in Texas, shared insights with her 111,000 TikTok followers, revealing that your body's scent can be largely predetermined by the ABCC11 gene. This gene is crucial for producing specific molecules that cause underarm odor, making some individuals more prone to body odor—especially after a workout or a long day at work—than others.

Variants of the ABCC11 Gene

There are two primary variants of the ABCC11 gene: GG and AA. Individuals carrying the GG variant are likely to emit a strong, unpleasant odor, whereas those with the AA variant tend to have virtually odorless sweat. A fascinating study of nearly 6,500 women discovered that only about 2% had the odorless AA variant.

Ancestry and Body Odor

But the influence of ancestry on body odor is equally intriguing. Research indicates that between 70 and 100 percent of individuals with European and African ancestry possess the odor-causing GG variant. Conversely, approximately 70 to 100 percent of those with Asian ancestry, particularly people of Chinese and Korean descent, carry the AA variant.

Sweat, Bacteria, and Scent

Understanding body odor isn’t only about the genes; it’s also about the way sweat interacts with the skin's bacteria. The apocrine sweat glands, commonly found in areas like the armpits and around the genitals, release odor precursors which, upon contact with bacteria, transform into strong-smelling compounds. The resulting scents can range from sulfur-like to musky or even urine-like.

Genetics and Body Odor

Although sweating is a natural human function, genetics significantly dictate whether or not that sweat will carry an odor. Those with the AA genotype are fortunate enough to produce fewer odor-causing molecules, leading to less pungent body odor. Dr. Madalyn Nguyen, an Oregon dermatologist, explains, "It's just going to be a lot less pungent and a lot less prevalent," suggesting that those with this variant might go longer without feeling the need to mask their body scent.

Deodorant Use and Genetics

Interestingly, deodorant preferences also link back to these genetic variations. A study revealed that women with the GG variant of the gene were 10 times more likely to use deodorant daily compared to their odor-free AA counterparts. However, even people with the AA variant still typically use deodorants due to socio-cultural norms, highlighting the complicated relationship between genetics and societal pressures regarding body odor management.

Hygiene Recommendations

To combat unwanted odor, dermatologists recommend simple yet effective hygiene methods. Dr. Kornmehl advises patients troubled by body odor to wash their armpits daily with products containing benzoyl peroxide or Hibiclens to eliminate odor-causing bacteria. Additionally, applying a clinical-strength antiperspirant at night can help reduce sweat production.

Beyond Body Odor: Earwax Consistency

Interestingly, the ABCC11 gene also has implications beyond just body odor – it affects earwax consistency as well! Those with the AA variant are more likely to have dry earwax, while those with the GG variant typically have stickier earwax.

The Demand for Deodorants

Although the AA variant is rare, the demand for deodorants remains robust. With the deodorant industry valued at over a billion dollars, the need for effective odor control transcends genetics. So, before you decide to skip that deodorant, it’s always a good idea to give yourself a sniff! What’s lurking underneath might surprise you!