Key Matchups to Watch

1. No. 5 Indiana at No. 2 Ohio State:

This clash features two top-ranked teams, but there are serious injury concerns impacting Ohio State. The Buckeyes recently lost their starting center and left tackle, leading to much-needed adjustments for their already shuffled offensive line. With Indiana's defensive line proving disruptive, Ohio State may face challenges they haven't dealt with all season.

However, the big question looms for the Hoosiers: can their offense keep up? Their schedule has been relatively weak, and their recent performance against Michigan (where they averaged only 1.67 points per possession) raises doubts about their ability to capitalize on Ohio State's injuries. The logical bet here appears to be the under, as both teams struggle to score. Pick: Under 51.5 (-106) via FanDuel.

2. No. 14 BYU at No. 21 Arizona State:

BYU's ranking faces scrutiny as it falls behind other one-loss teams despite having a strong resume. The Cougars matched up against Arizona State this week, which has been quietly impressive amidst a challenging schedule. Arizona State’s recent performances, especially their win over Kansas State, solidify their standing as favorites in this matchup.

With a standout running back in Cam Skattebo and an emerging quarterback in Sam Leavitt, the Sun Devils look to capitalize on BYU's comparative weaknesses. This game could dictate future rankings and provide clarity in the chase for a conference championship. Pick: Arizona State -3 (-110) via DraftKings.

Lock of the Week: No. 6 Notre Dame vs. No. 19 Army

The Fighting Irish demonstrated their prowess earlier this season, notably during a decisive win against Navy. While Army has had an impressive season at 10-0, they have yet to face a team of Notre Dame's caliber. Although I don't anticipate a blowout of 37 points as experienced before, the talent gap suggests Notre Dame prevails decisively. Pick: Notre Dame -14.5 (-110) via Caesars.

Underdog of the Week: Vanderbilt at LSU

As the season progresses, it's crucial to identify teams that might be waving the white flag. LSU, once a dominant force, faces a slump and potential morale issues after three consecutive losses. Meanwhile, Vanderbilt has consistently played the role of the spoiler. This mix could lead to an intriguing matchup, especially considering the trend of road underdogs performing well in SEC matchups. Pick: Vanderbilt +7.5 (-105) via BetMGM.

Under of the Week: Kentucky at No. 3 Texas

While the Wildcats are often overlooked, their defense stands tall nationally. Texas has struggled to score against formidable defenses, raising concerns over their ability to convert points in this matchup. Meanwhile, Kentucky has shown a knack for keeping scores low, making the under an attractive bet. Pick: Under 47.5 (-110) via Fanatics.

Over of the Week: Tulsa at South Florida

Expect a high-scoring spree between Tulsa and South Florida. Both teams have demonstrated a penchant for shootouts, and their previous offensive efforts hint that this game could see a flurry of points. Tulsa's average score output is impressive, making the over easily attainable here. Pick: Over 60.5 (-108) via FanDuel.

Final Note:

With the stakes at an all-time high, Week 13 is set to bring drama and excitement. The opportunities for bets abound, and as the season nears its climax, every game counts towards shaping the playoff picture. Engage with the matchups, analyze the odds, and let’s aim for a successful betting week!