
Skeletal Muscle Loss & Insulin Resistance: A Dangerous Duo for Heart Failure Risk in Older Adults
2025-04-09
Author: John Tan
Heart Failure: An Increasing Global Crisis
Heart failure (HF) is swiftly becoming the leading cause of deteriorating quality of life, especially among older adults, affecting more than 64 million individuals worldwide. Despite advancements in treatment, over 30% of HF patients succumb within a year of their diagnosis, while 60% don't survive beyond five years. Understanding the causes and prevention strategies is paramount.
The Link Between Muscle Loss and Heart Failure
Many patients with HF also suffer from muscular disorders like sarcopenia, marked by significant muscle mass loss that leads to functional impairment. Both conditions share similar biological mechanisms, including metabolic irregularities and inflammation, making it plausible to associate sarcopenia with heightened HF risk.