Health

Urgent Action Required: How a Two-Dose Vaccine Strategy is Battling Mpox in the DRC

2024-10-12

Author: John Tan

The Launch of the Mpox Vaccination Campaign

The Mpox vaccination campaign in the Democratic Republic of the Congo (DRC) has officially kicked off, marking a critical step in the country's fight against the Mpox outbreak. Launched on October 4, the initiative carries a strong message from Dr. Jean Kaseya, the Director General of Africa CDC: two doses are essential for optimal protection against the virus. While a single dose offers over 50% protection, Dr. Kaseya urges that, “We don’t want to compromise the health of our people.”

Goma: The Launching Point

Goma, a city heavily impacted by the outbreak, serves as the campaign's starting point. As concerns deepen over the rising number of Mpox cases, last reported in Ghana—now the 16th nation embroiled in the outbreak—the urgency of the situation becomes more pronounced. Despite the campaign's rollout, gaps in surveillance and testing persist across the affected countries. Alarmingly, testing positivity rates hover around 47%, with 43% of tests returning positive results, highlighting a critical need for enhanced screening measures.

Challenges in Surveillance and Testing

Dr. Kaseya elaborated on the challenges facing the campaign, including the inability to confirm suspected cases without comprehensive testing. He indicated the current track record for contact tracing is dismal; targeting 90% success, only about 4% of contacts have been traced thus far. "The performance of our surveillance systems is simply not sufficient," he stated.

Funding for the Response

In his weekly media briefing, Dr. Kaseya celebrated a major achievement: the funding for the Mpox response plan has exceeded its original target of $600 million, an essential boost in combatting the virus. However, he cautioned that to effectively curb the virus's spread, targeted interventions focused on vulnerable populations are paramount.

Prioritizing Vulnerable Populations

Given that the DRC is the most affected nation, priority is being given to healthcare workers, sex workers, children in high-risk areas, prisoners, displaced individuals, truck drivers, and those living with HIV. Truck drivers are particularly vulnerable due to their constant cross-border travels, accentuating the critically needed border surveillance throughout the Northern Corridor, which includes key nations like Kenya, Uganda, and Tanzania.

The Importance of Action

Dr. Kaseya made it clear that while testing remains a significant hurdle—impeded by issues such as sample collection inadequacies, laboratory capacity, and equipment quality—this should not stall decisive action. "Choosing to act only based on confirmed cases is simply not an option," he warned.

Impact on Children

Moreover, the impact of Mpox on children under 15 is particularly troubling, compounded by high rates of malnutrition in the region. The evolving nature of the virus—with its mutations—creates multiple outbreaks within one, further complicating the response. Early indications of mother-to-child transmission have surfaced, but Dr. Kaseya emphasized that comprehensive research into Mpox's epidemiology, which remains poorly understood, is vital for future control efforts.

Conclusion

This situation poses a profound public health challenge for the DRC and surrounding nations. The urgent implementation of effective vaccination strategies and robust surveillance systems can potentially stave off further escalation. As experts rally towards a solution, the time for action is now—before Mpox takes an even heavier toll.